PCR-Compatible Reagent for Rapid Buccal Swab Lysis
Reliable solution for fast and convenient DNA extraction, helping to streamline and accelerate genetic testing workflows.
MaGI-LysIT is an efficient lysis reagent designed for the rapid preparation of DNA samples from buccal epithelium. It is intended for use in protocols for determining biological relationships, as well as in screening and population studies.
The reagent’s formula contains PCR-compatible detergents that ensure highly effective cell lysis, inactivation of intracellular nucleases, and direct PCR amplification without additional purification steps.
Key Features:
Fast: Sample preparation takes only 15 minutes.
Simple: No purification required before PCR amplification.
Universal: Fully compatible with any STR kit.
Convenient: Optimized for standard sample types such as buccal epithelium.
Stable: Inactivation of nucleases enables extended sample storage at – 20 °C.
In forensic casework, especially sexual assault investigations, separating DNA from different sources is often the deciding factor for obtaining interpretable results. Vaginal swabs are particularly demanding: the overwhelming amount of female epithelial cells can mask the limited number of sperm cells.
An optimized buffer system enables selective lysis of epithelial cells while preserving sperm integrity, making it possible to recover male DNA even from complex mixtures.
Key Features:
Reliable and consistent separation of DNA fractions during differential lysis
Streamlined workflow: DNA preparation carried out in a single column, no additional pipetting required
Sterilized with ethylene oxide to ensure a product free from DNA, RNA, DNases, and RNases
Improved DNA recovery efficiency
Benefits for forensic laboratories:
Faster processing with fewer manual steps
Reliable male DNA profiles from challenging mixed samples
Lower contamination risk due to minimal sample handling
Easy integration with existing DNA extraction protocols
Stable: Inactivation of nucleases enables extended sample storage at – 20 °C.